DUBAI, United Arab Emirates — Iran's supreme leader on Wednesday rejected U.S. calls for surrender in the face of blistering Israeli strikes and warned that any military involvement by the Americans would cause "irreparable damage" to them, in recorded video aired by state TV. It was the ...

YOUNGSTOWN — A male, 18, was shot to death in the 900 block of Lanterman Avenue, not far from Lanterman’s Mill on the South Side, early today. It is being called a homicide. A Youngstown police press release states that officers were called to the the 900 block of Lanterman Avenue at 12:05 ...

KYIV, Ukraine — Emergency workers pulled more bodies Wednesday from the rubble of a nine-story Kyiv apartment building demolished by a Russian missile, raising the death toll from the latest attack on the Ukrainian capital to 28. The building in Kyiv's Solomianskyi district took a direct ...

WASHINGTON — The number of Americans applying for unemployment benefits dipped to 245,000 last week, hovering at historically low levels, the Labor Department said Wednesday. U.S. jobless claims ticked down from 250,000 the week before. Economists had expected last week's claims to match ...

All 50 U.S. states have agreed to the OxyContin maker Purdue Pharma 's latest plan to settle thousands of lawsuits over the toll of opioids. A judge on Wednesday is being asked to clear the way for local governments and individual victims to vote on it. Government entities, emergency room ...

BELLE PLAINE, Minn. (AP) — The man suspected of shooting two Minnesota lawmakers, killing one of them, has been taken into custody, two law enforcement officials said. Vance Boelter was arrested Sunday evening. The arrest was confirmed to The Associated Press by law enforcement officials were ...